L-Glutathionine (600mg x 60 Capsules)

SKU: 9351648004679
Regular price $60.00 USD
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Product details

  • Vendor p1peptides
  • SKU 9351648004679
  • Barcode 9351648004679

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L-Glutathione (GSH) is a biologically active tripeptide composed of three amino acids — gamma-L-glutamyl-L-cysteinyl-glycine — containing a sulfhydryl (thiol) group that functions as a reducing agent in controlled research systems. It is recognized in scientific literature as the principal endogenous antioxidant within mammalian cells, playing a fundamental role in maintaining intracellular redox homeostasis under defined experimental conditions.


Molecular Characteristics & Research Applications

Experimental data from controlled laboratory settings document L-Glutathione's involvement across several key cellular defense and metabolic signaling pathways, including:

  • Direct reactive oxygen species (ROS) neutralization pathway dynamics and redox homeostasis research
  • Exogenous antioxidant regeneration mechanism studies including Vitamin C and Vitamin E pathway interactions
  • Glutathione peroxidase enzyme cofactor activity and associated biochemical pathway investigation
  • Oxidative stress mitigation pathway modeling in controlled preclinical research systems
  • Phase II xenobiotic detoxification mechanism research
  • Cellular proliferation signaling pathway endpoint analysis
  • Apoptosis signaling pathway dynamics and programmed cell death mechanism research
  • Intracellular redox balance regulation and sulfhydryl biochemistry investigation

These distinct metabolic pathway interactions make L-Glutathione a valuable investigative tool in laboratory research examining oxidative stress biology, detoxification mechanisms, and redox-dependent cellular signaling under controlled experimental conditions.


Purity & Quality

  • ≥99% Purity — HPLC Verified
  • Independently tested by accredited third-party laboratory
  • Certificate of Analysis (CoA) available for every batch

Research Use Only (RUO) Notice

All products are furnished strictly for in-vitro laboratory research use only. These materials are not medicines or drugs and have not been evaluated or approved by the U.S. Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease or medical condition. Introduction into humans or animals is strictly prohibited. Not for human, medical, diagnostic, or veterinary use.

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L-Glutathione (GSH) — Full Product Page (Detailed Version)

Product Title:
L-Glutathione (GSH) — Reduced Tripeptide Antioxidant Research Compound (600mg)

Short Description:
A high-purity endogenously occurring tripeptide serving as the principal intracellular thiol-based antioxidant in mammalian tissue, investigated in preclinical research for redox homeostasis modeling, phase II xenobiotic detoxification pathway research, enzymatic cofactor activity analysis, and oxidative stress signaling investigation. ≥99% Purity, HPLC-Verified. Third-Party CoA Included. For in-vitro laboratory research use only.

Full Product Description:

Overview

L-Glutathione (γ-L-glutamyl-L-cysteinylglycine) is a ubiquitous endogenously produced tripeptide serving as the principal intracellular thiol-based antioxidant in mammalian tissue. It plays a fundamental role in maintaining cellular redox homeostasis, mediating phase II detoxification of xenobiotics, and regulating signal transduction pathways in controlled experimental systems. P1 Peptides provides this compound in a high-purity 600mg encapsulated format to support precise experimental applications in oxidative stress modeling and enzymatic cofactor analysis research.

Biochemical Characteristics

  • Chemical Name: L-Glutathione (Reduced)
  • Sequence: γ-Glu-Cys-Gly
  • Molecular Formula: C₁₀H₁₇N₃O₆S
  • Molecular Weight: 307.32 g/mol
  • CAS Number: 70-18-8
  • PubChem CID: 124886
  • Purity: ≥99% (HPLC Analyzed)
  • Solubility: Soluble in water
  • Appearance: White crystalline powder (Encapsulated)

Mechanism of Action in Research Systems

The biochemical activity of L-Glutathione in experimental systems is derived from the sulfhydryl (thiol) group of its cysteinyl residue, which functions as a nucleophile in conjugation reactions and as a reducing agent in redox reactions under controlled laboratory conditions.

Redox Buffering Pathway Activity
In controlled experimental systems, GSH directly interacts with reactive oxygen species (ROS) including hydroxyl radicals and superoxide anions, providing a research model for investigating lipid peroxidation prevention and DNA oxidative damage pathway dynamics.

Enzymatic Cofactor Research
GSH serves as an essential substrate for glutathione peroxidase (GPx) and glutathione S-transferase (GST) — enzymes critical for peroxide neutralization and toxin solubilization pathway research in controlled laboratory settings.

Disulfide Bond Regulation Research
GSH modulates the reduction of disulfide bonds in proteins in experimental systems, providing a research framework for investigating protein folding dynamics and the activity of redox-sensitive transcription factors including NF-κB and AP-1 signaling pathways.

Research Applications

In biochemical and preclinical research settings, high-concentration L-Glutathione (600mg) is utilized to investigate the following experimental areas:

Hepatoprotective Pathway Research
Laboratory investigation of liver detoxification pathway dynamics and drug-induced hepatotoxicity mitigation mechanisms in controlled experimental systems.

Cellular Aging & Apoptosis Research
Examining correlations between intracellular GSH depletion and the activation of apoptotic signaling cascades in defined cell-based research models.

Melanogenesis Pathway Research
Investigating the mechanistic basis by which glutathione interacts with tyrosinase activity and influences melanin synthesis pathway dynamics — specifically the biochemical shift between eumelanin and pheomelanin production pathways — in controlled in-vitro research systems.

Immune Signaling Research
Analyzing the role of intracellular thiol status in lymphocyte proliferation pathway dynamics and immune response signaling efficacy in controlled laboratory environments.

Product Specifications

  • Concentration: 600mg per capsule
  • Format: 60 Capsules — Encapsulated lyophilized powder
  • Storage: Store at room temperature (20–25°C), protected from direct light and moisture

Purity & Quality

  • ≥99% Purity — HPLC Verified
  • Independently tested by accredited third-party laboratory
  • Certificate of Analysis (CoA) available for every batch

Research Use Only (RUO) Notice

All products are furnished strictly for in-vitro laboratory research use only. These materials are not medicines or drugs and have not been evaluated or approved by the U.S. Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease or medical condition. Introduction into humans or animals is strictly prohibited. Not for human, medical, diagnostic, or veterinary use.