{"product_id":"cjc-1295-no-dac-5mg","title":"CJC-1295 no DAC 5mg","description":"\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eCJC-1295 (No DAC), also referenced in scientific literature as Modified GRF(1-29) or Mod GRF 1-29, is a synthetic analog of growth hormone-releasing hormone (GHRH) designed for research into pulsatile growth hormone (GH) secretion dynamics and somatotropic axis regulation. This 29-amino acid peptide represents a truncated and amino acid-substituted version of native GHRH, engineered with enhanced resistance to enzymatic degradation while maintaining physiological pulsatility characteristics relevant to controlled research models.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eMolecular Characteristics \u0026amp; Research Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eIn experimental biology, CJC-1295 (No DAC) is utilized to investigate mechanisms governing endogenous GH release patterns, hypothalamic-pituitary signaling, and downstream anabolic cascades. Its selective activation of growth hormone-releasing hormone receptors (GHRH-R) on anterior pituitary somatotrophs — without the extended half-life conferred by Drug Affinity Complex (DAC) modification — enables researchers to study natural pulsatile GH secretion dynamics under controlled laboratory conditions.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eKey research applications include examination of the following molecular pathways and processes:\u003c\/p\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003ePulsatile GH secretion dynamics and circadian rhythm preservation\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eHypothalamic-pituitary axis signaling and receptor-mediated signal transduction\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eGHRH-R activation and downstream somatotropic pathway activity\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eInsulin-like growth factor-1 (IGF-1) mediated cascade modeling\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eGH secretagogue biology and somatotropic function research\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eAnabolic tissue response pathway investigation\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eMetabolic substrate utilization and lipolytic signaling mechanisms\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eProtein synthesis pathway activity under defined experimental conditions\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eAge-related changes in somatotropic axis function across multiple experimental models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003ePurity \u0026amp; Quality\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003e≥99% Purity — HPLC Verified\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eIndependently tested by accredited third-party laboratory\u003c\/li\u003e\n\u003cli class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eCertificate of Analysis (CoA) available for every batch\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eResearch Use Only (RUO) Notice\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eAll products are furnished strictly for in-vitro laboratory research use only. These materials are not medicines or drugs and have not been evaluated or approved by the U.S. Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease or medical condition. Introduction into humans or animals is strictly prohibited. Not for human, medical, diagnostic, or veterinary use.\u003c\/p\u003e","brand":"p1peptides","offers":[{"title":"Default Title","offer_id":52862352130232,"sku":"9351648004709","price":65.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0932\/8790\/7512\/files\/variant-16.jpg?v=1771487008","url":"https:\/\/p1peptides.com\/products\/cjc-1295-no-dac-5mg","provider":"p1peptides","version":"1.0","type":"link"}